ABC News February 11, 2019

Everything you need to know about Ebola

WATCH: What is Ebola?

The current Ebola outbreak in the Democratic Republic of the Congo is the second largest in history and the worst the country has ever seen.

At least 811 people have reported symptoms of hemorrhagic fever in the Central African nation's eastern provinces of North Kivu and Ituri, which share borders with South Sudan, Uganda and Rwanda.

Among those patients, 750 have tested positive for Ebola virus disease, according to a daily bulletin from the country's health ministry on Sunday night.

There have been 510 deaths thus far, including 449 people who died from confirmed cases of Ebola. The other deaths are from probable cases of Ebola.

"No other epidemic in the world has been as complex as the one we are currently experiencing," the country's health minister, Dr. Oly Ilunga Kalenga, said in a statement Nov. 9.

(MORE: Nearly 100 children dead as world's 2nd-largest Ebola outbreak surpasses 800 cases)

The rising number of cases in the ongoing epidemic has far exceeded that of the 2000 outbreak in Uganda, making it second only to the 2014-2016 outbreak in multiple West African nations that infected more than 28,000 people, according to data from the U.S. Centers for Disease Control and Prevention.

The World Health Organization (WHO), the global health arm of the United Nations, has deemed the risk of transmission in the current outbreak "very high" at the national and regional levels, while the risk globally remains low. Still, the organization concluded in October that the outbreak does not yet meet the criteria for an international public health emergency -- a proclamation that would have mobilized more resources and garnered global attention.

(MORE: Ebola outbreak in Democratic Republic of Congo now 2nd worst in history)

Here is what you need to know about the deadly virus.

Aboulaye Cisse/WHO
Social mobilizers put up an Ebola poster in Tchomia to raise awareness in the local community in the Democratic Republic of Congo, Oct. 9, 2018.

What is Ebola?

The Ebola virus is described as a group of viruses that cause a deadly kind of hemorrhagic fever. The term "hemorrhagic fever" means it causes bleeding inside and outside the body.

(MORE: Democratic Republic of Congo's current Ebola outbreak worst in country's history, officials say)

The virus has a long incubation period of approximately eight to 21 days. Early symptoms include fever, muscle weakness, sore throat and headaches.

As the disease progresses, the virus can impair kidney and liver function and lead to external and internal bleeding. It's one of the most deadly viruses on Earth with a fatality rate that can reach between approximately 50 to 90 percent. There is no cure.

(MORE: Congo approves more experimental Ebola treatments in race to contain growing outbreak)

The WHO has received approval to administer an experimental Ebola vaccine, using a "ring vaccination" approach, around the epicenter of the current outbreak in the Democratic Republic of the Congo. More than 77,000 people, including children as well as health and frontline workers, have been vaccinated in the outbreak zone since Aug. 8, according to the country's health ministry.

The vaccine, which was developed by American pharmaceutical company Merck, has proved effective against the country's previous outbreak in the western province of Equateur.

Junior Kannah/WHO
An ampule of one of the new therapeutics in Beni, the Democratic Republic of the Congo on Aug. 25, 2018.

How is it transmitted?

The virus is transmitted through contact with blood or secretions from an infected person, either directly or through contaminated surfaces, needles or medical equipment. A patient is not contagious until they start showing signs of the disease.

Thankfully, the virus is not airborne, which means a person cannot get the disease simply by breathing the same air as an infected patient.

(MORE: Congo's latest Ebola outbreak could become 'worst ever' in East Africa, IRC warns)
Nyka Alexander/WHO
The new therapeutics are administered in these Biosecure Emergency Care Units for outbreaks (CUBE) at ALIMA Ebola treatment center in Beni General Hospital on Aug. 16, 2018.

Where have people been infected?

In this current outbreak, people have been infected in North Kivu and Ituri, which are among the most populous provinces in the Democratic Republic of the Congo and share borders with Rwanda, Uganda and South Sudan.

Those two provinces are awash with conflict and insecurity, particularly in the mineral-rich borderlands where militia activity has surged in the past year, all of which complicates the response to the outbreak. There is also misinformation and community mistrust of the medical response, partly due to the security situation, and some residents delay seeking care or avoid follow-up.

Ebola is endemic to the Democratic Republic of the Congo. This is the 10th outbreak the country has seen since 1976, the year that scientists first identified the deadly virus in the small northern village Yambuku near the eponymous Ebola River.

This outbreak in the country's eastern region was announced Aug. 1, just days after another outbreak in the western part of the country that killed 33 people (including 17 who had confirmed cases of Ebola) was declared over.

(MORE: Ebola survivors suffer 'severe' neurological and psychiatric effects, new study finds)
Junior Kannah/WHO
WHO Epidemiology Team Leader Dr. Marie-Roseline Darnycka Bélizaire interviews a woman as part of the process of Ebola contact tracing on Aug. 26, 2018, in Mangina, Democratic Republic of the Congo.

Where did the virus come from?

The dangerous virus gets its name from the Ebola River in northern Democratic Republic of the Congo, which was near the site of one of the first outbreaks. The virus was first reported in 1976 in two almost simultaneous outbreaks in areas that are now South Sudan and the Democratic Republic of the Congo. The outbreaks killed 151 and 280 people, respectively.

(MORE: At the center of Ebola in the Congo, worry and indifference coexist)

Certain bats living in tropical African forests are thought to be the natural hosts of the disease. The initial transmission of an outbreak usually results from a wild animal infecting a human, according to the WHO. Once the disease infects a person, it is easily transmissible between people in close contact.

An outbreak that began in the West African nation of Guinea in March 2014, and soon spread to neighboring Liberia and Sierra Leone, was the largest in history, infecting 28,652 people and causing 11,325 deaths. The outbreak, which the WHO deemed a public health emergency of international concern, was declared over in June 2016.

(MORE: Experimental vaccine approved for use against Ebola virus in Congo)
Nyka Alexander/WHO
Health workers at Mangina hospital prepare to conduct a safe burial, Aug. 15, 2018.

Who is at risk?

The virus is not airborne, which means those in close contact can be infected and are most at risk. A person sitting next to an infected person, even if they are contagious, is not extremely likely to be infected.

However, health workers and caregivers of the sick are particularly at risk because they work in close contact with infected patients during the final stages of the disease, when the virus can cause internal and external bleeding.

In the current outbreak alone, 67 health workers have been infected so far and at least 22 of them have died, according to the WHO.

(MORE: 'Young miracle' newborn recovers from Ebola after mom dies in childbirth in world's 2nd deadliest outbreak)

There are also a high number of young children infected in the current outbreak. Children, who are at greater risk than adults of dying from Ebola, account for more than one-third of all the cases, while one in 10 Ebola patients is a child under the age of 5, according to the United Nations International Children's Emergency Fund.

"We are deeply concerned by the growing number of children confirmed to have contracted Ebola," Marie-Pierre Poirier, UNICEF's regional director for West and Central Africa who returned this week from Beni, said in a Dec. 12 statement.